Vol. 2 & Issue 1 ; Section A : Chemical Sciences

Date : Nov.2011 to Jan.2012

 

Synthesis and Spectral Characterization of Mn(II), Zn(II) and Cd(II) Complexes with Thiosemicarbazone as Primary Ligand and 2,2'–Bipyridyl as Secondary Ligand

Rakhi Chaudhary and Shelly

  • Abstract

    Complexes of Mn(II), Zn(II) and Cd(II) with 2,5–Dihydroxy butyrophenone thiosemicarbazone(L1)/2,5–Dihydroxy benzophenone thiosemicarbazone(L1’) as primary ligands and 2,2'–bipyridyl(L2) as secondary ligand have been isolated and characterized by elemental analysis, molar conductance, magnetic measurements, electronic spectra, IR spectra and thermogravimetric analysis. Conductivity data of the complexes in DMSO suggested their non‐electrolytic nature. The molecular weight of the complexes determined by the Rast Camphor method corresponds with the weight of the formula, indicating their monomer nature. TG analysis confirms the presence of one coordinated water molecule in all the complexes. On the basis of above observations the complexes are proposed to be octahedral in nature.

Effect of pH on the formation of complex compounds with Schiff bases derived from 3-aldehydosalicylic acid with 7-amino-4-methyl coumarin

Basavaraj M. Kalshetty, S.S.Suvarnakhandi, R.C.Sheth and M.B.Kalashetti 

  • Abstract

    The complex compounds of metal ions like Cu (II), Ni (II), Co (II), Cd (II), with the Schiff base ligand LHhave been synthesized at different pH ranges. The synthesized complex compounds have been characterized on the basis of elemental analysis, molar mass and IR spectral studies. Hence, the study reveals that the ligand LH2 (Scheme 1) behaves as a monobasic bidentate ON donor where the two structures suggest the non-involvement of carboxylic oxygen atom in coordination at pH= 3-4. The ligand LH2 behaves as dibasic tridentate OON donor, suggesting the non-involvement of carbonyl oxygen atom of coumarin in the complex compounds at pH= 7. The ligand LH2 behaves as a dibasic tetra dentate OONO donor at pH=8, suggesting the coordination of coumarin carbonyl oxygen atom to the metal ions in the complex compounds.

Equilibrium Studies on Mixed Ligand Complexes of Drug Phenylpropanolamine Hydrochloride with Chromium and Cobalt Metal Ions

Pragati M. Deore, Bhimrao C.Khade, Arun Khalkar and B.R. Arbad

  • Abstract

    Equilibrium studies on metal-ligand complex equilibria involving Chromium and Cobalt metal ions with drug, Phenylpropanolamine Hydrochloride with Amino acids Glycine and Glutamine in 80% (v/v) ethanolwater mixture at 300C ± 0.10C and ionic strength of 0.1M (NaClO4 ) has been studied. Formation of complex species with respect to pH have been discussed by Irving-Rossotti technique and evaluated by SCOGS computer program.

DFT based study of charge transfer and interaction energy between phenyl tin (IV) chlorides and derivatives of pyridine-Part II

P. P. Singh, R. K. Singh and Ramesh Chandra Sharma

  • Abstract

    Interaction of phenyl tin(IV) chlorides have been discussed with eleven ortho, meta and para derivatives of pyridine with total number of 99 interactions. Phenyl tin(IV) chlorides form most stable complexes with ortho, meta and para derivatives of phenylacetatopyridine and least stable complexes with ortho, meta and para derivatives of nitropyridine. The order is ortho > meta > para. Best interaction is shown by C6H5SnCl3 with cyanopyridine-o as in this case SA ? SB.

Microwave mediated Solid phase synthesis of N-phenyl- 3-(substituted phenyl)-5-aryl-2  pyrazolines and their antibacterial activity

Sheetal Shaktawat, Anju Devpura, Mangalshree Dulawat, Jayant P. Singh, Sumer S. Chundawat and Shiv S. Dulawat

  • Abstract

    An ecofriendly approach for the synthesis of title compounds using inorganic solid support for its catalytic role as well as an energy transfer medium is described. In this methodology pyrazolines have been synthesized by Michael addition reaction under Microwave irradiation using Alumina as solid support. The reaction time is brought down from hours to minutes along with yield enhancement. The structures of these compounds were established by elemental analysis and spectral data. All the synthesized compounds were tested for their in vitro antibacterial activity. Some compounds showed significant antibacterial activities

Bombax Ceiba flower extract: Biological screening and application as pH indicator

Pathan Mohd Arif Khan, Syed Hussainb, Mohd Mohsina, Mazahar Farooquic, Ahmed Zaheera

  • Abstract

    New flavone has been isolated from the flower extract Bombax Ceiba. The isolated compound is separated and identified using mass, NMR, IR and UV. The compound is tested for suitability as an indicator for acidbase, complexometric and redox titrations. Titration error, relative error and percentage error has been calculated for different set of titrations viz strong acid-strong base, strong acid-weak base, weak acidstrong base, weak acid –weak base. Isolated compound is also screened for its antibacterial and anti fungal activity

A study of fluoride and their removal through adsorption from ground water of Rajgarh (block) M.P.INDIA

Choubey O.N. and Agrawal G.D.

  • Abstract

    A survey was carried out to evaluate the status of fluoride content in drinking water sources of villages of Rajgarh District M.P. The water samples were collected from the hand pumps of 15 villages of Rajgarh (Block) in summer season. The result revealed that fluoride content in all samples ranges between 2.5 to 4ppm. The adsorption of fluoride on different adsorbents was investigated in the present study. The adsorption of fluoride on adsorbents was found to follow Freundlich and Langmuir isotherm1.

Heavy Metals Contamination in Sediments of the River Parbati, Baran, Rajasthan

M.K.Jain, L.K.Dadhich and Kalpana S.

  • Abstract

    The concentrations of nine heavy metals (Fe, Zn, Ni, Cu, Cd, Cr, Pb, Mn and Co) were determined in riverbed sediments collected from selected ten locations on River Parbati in Baran district of Rajasthan in pre-monsoon season in consecutive three years (2008 to 2010) to evaluate their levels and distribution along river length. The ranges of the measured concentrations in the riverbed sediments on dry basis are as follows: Fe: 0.35-0.88%; Zn: 49.0-106.7mg/kg; Ni: 4.2-18.3mg/kg; Cu: 19.8-68.2mg/kg; Cd: 0.20- 0.75mg/kg; Cr: 5.7-14.9mg/kg; Pb: 1.1-7.3mg/kg; Mn: 37.5-138.9mg/kg and Co: 0.90-3.8mg/kg on dry weight basis. To assess metal contamination in sediment, US Environmental Protection Agency’s (USEPA) guidelines were applied. To evaluate the origin Pearson Correlation Coefficient was calculated, which shows that there are no significant correlations among these metals, indicating that they have different anthropogenic and natural sources.

Microwave assisted improved synthesis and antibacterial activity of some 1-acetyl-3, 5-diaryl- 2 –pyrazolines

Jayant P. Singh, Vikash Tiwari, Sumer S. Chundawat, Anju Devpura, Neetu Jaitawat,Mangalshree Dulawat, Shiv S. Dulawat

  • Abstract

    Microwave induced solvent-free solid phase synthesis of 1-acetyl-3,5-diaryl- Δ2 –pyrazolines has been achieved by the cyclocondensation of substituted chalcones (1a-f) with hydrazine hydrate (2) followed by acetic acid in the presence of alumina under solvent free condition using domestic microwave oven has been described. The process has advantage over conventional methods such as shorter reaction time, higher yield and environmental acceptability. The structures of these compounds were established by elemental analysis and spectral data. All the synthesized compounds were tested for their in vitro antibacterial activity. Some compounds showed significant antibacterial activities.

Study of stability constant of biological active molecules (drug) using potentiometric titration technique

Abdulbaset . Zaida, Mazahar Farooquia, D.M. Janraoc

  • Abstract

    In this review article, we described the study of stability constant of some biological active molecules with various metal ions by potentiometric titration technique. The literature survey reveals that the compounds contains donor group are extensively used in biology and medicinal chemistry. The metal chelates of donor groups are also used, in view of the great analytical, biological, industrial and manifold uses of donor groups complexes with metal ions.

Synergistic effect of DTPMP in well water by sodium tungstate-Zn2+ system

S.Agnesia Kanimozhi and S.Rajendran

  • Abstract

    The aim of this present work is to study, the corrosion behavior of carbon steel in well water in the presence of sodium tungstate (ST)-Zn2+- Diethylenetriamine entamethylene phosphonicacid (DTPMP). Weight loss study has been employed tom evaluate the inhibition efficiency of this system. It was found that the inhibition efficiency (IE) of ST (50 ppm)-Zn2+ (10 ppm) was improved from 8% to 82% by the addition of 150 ppm of DTPMP. Surface film has been analysed by FTIR spectroscopy, UV florescence and SEM analysis. The protective film consists of Fe2+-WO4 2-, Fe2+-DTPMP complex on anodic site and Zn (OH)2 complex at cathodic site. It is found to be UV florescent. A mechanism for the inhibition of corrosion is proposed based on the above results.

Thermal profile and decomposition kinetics of some new Schiff bases derived from 4-amino antipyrine

Shipra Baluja, Jagdish Movaliya and Ashish Patel

  • Abstract

    Thermal properties of some new Schiff bases derived from 4‐amino antipyrine and different aromatic aldehydes have been studied by TGA, DTA and DSC methods. Thermal analysis of these bases were done along with the evaluation of some kinetic parameters such as energy of activation (E), frequency factor (A), order of reaction (n) and entropy of activation (ΔS).

Manganese acetate: as an efficient environmentally benign catalyst for acetylation of phenols

V. P. Sondankara, V. B. Deshmukha, K. R. Rathoda and S. R. Bhusare

  • Abstract

    Phenols were efficiently acetylated with acetic acid in the presence of catalytic amount of manganese acetate at reflux condition in high yields. The process is efficient and eco-friendly in the sense that it avoids the use of acetyl chloride or acetic anhydride and is percent atom economical.

Ultrasonic velocity studies of solutions of some organic compounds at 298.15 K

Shipra Baluja and Falguni Karia

  • Abstract

    The density, viscosity and sound velocity of 1-H-benzimidazole and 2- methyl benzimidazole derivatives in methanol and chloroform solutions have been studied at 298.15 K over a wide range of concentration. From these experimental data, some acoustical parameters such as intermolecular free length (Lf), isentropic compressibility (κs), relaxation strength (r), internal pressure (p) and free volume (Vf) have been evaluated. A fairly good correlation between a given parameter and concentration is observed. The results are interpreted in terms of molecular interactions like solvent-solvent, solvent-solute and solutesolute interactions.

Equilibrium studies on mixed ligand complexes of transition metal ions with Tazobactum (antibiotics) drug and amino acids

B. K. Magarea and M. B. Ubaleb

  • Abstract

    Equilibrium studies on mixed ligand complexes of transition metal ions with tazobactum ,an antibiotics drug (L) and a series of eight amino acids(R) have been carried out at 27 0C temperature and 0.1 M ionic strength (NaClO4) in aqueous solution. The formation of complex species has been evaluated by computer program and discussed in terms of various relative stability parameters.

Synthesis and crystal structure of 4-((2-aphthalen-1-yl)- diazenyl) benzenesulfonamide

Ali BENOSMAN, HassibaBOUGUERRIA, Abdelkader BOUCHOUL andSalah Eddine BOUAOUD

  • Abstract

    The unsymmetrical azo-compound namely 4-((2-hydroxynaphthalen-1-yl) diazenyl) benzeneesulfonamide was synthesized and isolated as crystal reddish-orange needles. Crystal structure determination was occurred by X-ray diffraction. Resolution of structure shows a dimer of formula C32H26N6O6S2 which crystallizes in space group P21 / a, monoclinic system with: a = 7.4033Å, b = 15.1317Å c = 26.2888Å; α =90.00°, β = 95.1787 °, γ =90.00°.

De-escalation of Concentration of Fluorides by Clayware with Alum Salts in Potable Water

Mohana Rao Abburi, Divya Jyothi.M, H.K.R.Prasad. s, Vinod. P and Zeneba Tedasse

  • Abstract

    For de-escalation of fluorides in the potable water, we have enumerable de fluoride techniques of which flocculation, Coagulation, Electro Coagulation, Adsorption, Absorption, have been taken a vital path. This research where it has been successfully adopted by the researchers took place at highlands around 3000 ft from the sea level in Ethiopia Country. We identified various concentrations of fluoride in the ground water around Aksum town of Ethiopia. Aluminum Ammonium Sulphate clayware is the one of the vital methods in the community at economical sustainability for de-escalation of the fluorides in the potable waters. The villages which are surrounded by the Aksum city of Ethiopia have been identified as fluoride contaminated areas and the people of these places (woredas) have been excruciating for the last 25-30 years vigorously with the Fluorosis. Here we concentrate predominantly Longmuir studies to carry this Proposal.

Kinetics of the reaction of o-Hydroxy benzaldehyde with m-anisidine

Bhausaheb K. Magara, Vijay N. Bhosalea , Anil S. Kirdantb, Trimbak K. Chondhekarc

  • Abstract

    The rate of formation of Schiff base from o-Hydroxybenzaldehyde with m-anisidine has been reported in ethyl alcohol at room temperature. The order of reaction is second. The rate of reaction is first order with respect to o-Hydroxy benzaldehyde and first order with respect to manisidine. Suitable reaction mechanism has been suggested for the formation of the Schiff base.

Impact of Abattoir Effluent on River Landzu, Bida, Nigeria

Mohammed Saidu and John Jiya Musa

  • Abstract

    This study assesses the impact of Abattoir effluent on the physico‐chemical parameters of Landzu River. Water samples were collected from four different sampling point; P1, P2, P3 and P4, it was collected at both the upstream and downstream of the effluent point of discharge. The parameters tested were pH, Dissolve Oxygen, Suspended Solids, Electrical Conductivity, Manganese, Chloride, Copper, Iron and standard method of water and wastewater analysis were used and compared with WHO permissible limit. The results shows that virtually all the sample were above the WHO standard which make the river water to be unsafe to both Human and aquatic life. There is need to upgrade the present abattoir to reduce it level of pollution

Synthesis and Characterization of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes with 4-{(E)-[(2-chlorophenyl) imino] methyl} benzene-1,2-diamine

K. George Abraham, Manohar V. Lokhande and Sudhakar Bhusare

  • Abstract

    The complexation of a series of new Schiff bases containing 4-{(E)-[(2-chlorophenyl)imino]methyl}benzene- 1,2-diamine moiety with some transition metal ions like Mn(II), Co(II), Ni(II) Cu(II)and Zn(II) with general stoichiometric ratio is 1:2 and molecular formula is [M(L2)nH2O]X [ where M= Mn(II), Co(II), Ni(II) Cu(II)and Zn(II)L= 4-{(E)-[(2-chlorophenyl)imino]methyl}benzene-1,2-diamine and X= Cl, Br, I] have been synthesized and characterized by elemental analyses, molar conductance measurements, magnetic susceptibility and spectral techniques like IR, UV-Visible, Mass ,TGA/DTA, ESR & X-ray powder diffraction. The complexes were found octahedral geometry. The mass spectral data confirms the monomeric structure of the metal complexes while the TGA/DTA studies confirm the presence of two water molecules in the complexes. The covalency factor (β), bonding parameter (b1/2) suggest the covalent nature of the complexes. The free Schiff base and its complexes have been tested for their antibacterial as well as antifungal activity by using disc diffusion method are discussed.

Kinetic and Degradation Studies of Organic Compound in Photo catalytic Reactors

S Feroz, Anna Jesil, Baqir Al Lawati, Ahmed, L.Nageswara Rao

  • Abstract

    An experimental investigation was carried out in photocatalytic reactors exposed to artificial UV source to study the kinetic and degradation of model organic compound benzoic acid. The apparent rate constant was determined in two different situations where either the concentration of organic compound or catalyst is kept constant in a batch reactor. The effect of concentrations and the dosage of photocatalyst on the degradation of benzoic acid in batch and continuous tank reactor were investigated

Kinetics and Mechanism of Hydrolysis of N-Salicylidene -p-methylaniline Spectrophotometrically

Anil S. Kirdanta, Bhausaheb K.Magarb and Trimbak K. Chondhekarc

  • Abstract

    Kinetics of hydrolysis reaction of the Schiff base, N‐ salicylidene ‐p‐methyl aniline (HL) have been studied in the pH range 2.86‐12.30 at temperature range 293‐308 K. A rate profile diagram of pH v/s rate constant shows the rate minimum in the pH range 4.51‐10.42 and reaches a plateau at pH > 10.73. Suitable reaction mechanism has been suggested for the hydrolysis of the Schiff base in acidic, neutral and basic medium. From the effect of temperature on the rate, various thermodynamic parameters have been evaluated

Corrosion behavior of 304-stainless steel in aqueous sulphate Environment

P.Selvakumar and G.T.Parthiban 

  • Abstract

    In different industries Stainless steel corrode in different environments. The various environments can affect the metal to different extents. The effect of pH and concentration of Aluminium sulphate in aqueous environment has been studied. The potentiodynamic polarization experiment was carried out at 0.003M, 0.03M and 0.15M concentration with the pH values of 5, 7, 9, 11, and 12.5. Weight loss experiment was also carried out at 0.003M, 0.03M and 0.15M concentrations. The results from potentiodynamic polarization technique indicate that when the pH value increases, corrosion potential shifts towards less negative values. Hence the metal becomes less susceptible to corrosion. Corrosion rate determined from the corrosion current density was compared with those obtained by weight loss method. From the above studies, it is observed that the corrosion of stainless steel is decreased with decrease in the concentration of Aluminium sulphate (0.003M to 0.15M) at constant pH or with increase in pH at constant concentration.

Effect of phase inversion and rheological factor on formation of asymmetric polyethersulpone ultrafilteration membranes for separation of metal ions

S. Velu and L. Muruganandam

  • Abstract

    Asymmetric ultrafiltration (UF) membranes were prepared from poly (ether sulfone) (PES) using N, N–dimethylformamide (DMF) solvent by phase inversion method. Solution cast PES membranes were homogeneous for all studied compositions, 12.5 to 20 % polymer and 87.5 to 80 % of solvent. The fabricated membranes were characterized for their UF performance such as pure water flux, water content and membrane hydraulic resistance and found to be moderate changes. It is estimated that the pure water flux of 20 % PES membrane increases from 12 to 76 l/m2.h, when the polymer concentration was decreased to 12.5 % in the casting solution. The membranes were also characterized for their separation performance through metal ions in aqueous solution. The percentage rejection of metal ions was increased while the permeate flux has decreasing trend.

Computational Investigations on the Corrosion Inhibition efficiency of some Pyridine based alkaloids

P.Udhayakala and T.V. Rajendiran b

  • Abstract

    The adsorption mechanism and inhibition performance of two pyridine based derivatives 4-methoxy-1- methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile(C1) and 4-methoxy-2-oxo-1,2-dihydropyridine-3 carbonitrile (C2) were investigated using Density functional theory (DFT) at the B3LYP/6-31G(d,p) basis set level in order to elucidate the different inhibition efficiencies and reactive sites of these compounds as corrosion inhibitors. The calculated results are in agreement with the experimental data. The calculated quantum chemical parameters correlated to the inhibition efficiency are EHOMO (highest occupied molecular orbital energy), ELUMO (lowest unoccupied molecular orbital energy), the energy gap(ΔE), hardness(η), Softness(S), dipole moment(μ), electron affinity(EA), ionization potential(IE), the absolute electronegativity (χ) and the fraction of electron transferred (ΔN). The local reactivity has been studied through the Fukui and condensed softness indices in order to predict both the reactive centres and to know the possible sites of nucleophilic and electrophilic attacks.

Synthesis and Spectral Studies of Metal Complexes of Substituted 2−Hydroxy Acetophenones−2− Pyridinyl Hydrazones

Suresh Pal and R.S. Chauhan

  • Abstract

    Metal complexes of Substituted 2Hydroxy Acetophenones 2 Pyridinyl Hydrazones were synthe- sized by refluxing a solution of appropriate ligand (1 m mol) in boiling ethanol (20 ml) with a solution of metal salt (1 m mol) in ethanol (20 ml) or an aqueous solution of K2PtCl4 (1 m mol) for two hours. The coloured crystalline solids of various shades were separated from the resulting solution at room temperature. The solids were filtered off washed with ethanol and diethyl ether and dried over P4O10 under vacuum. Synthesized complex have characterized by elemental analysis, molar conductance, magnetic and spectral studies. Complexes are stable at room temperature and can be stored for a sufficient time without decomposing. All the complexes are freely soluble in DMF and DMSO.