Vol. 4 & Issue 3 ; Section A : Chemical Sciences

Date : May. to Jul.2014

 

Enhance C5+ Recovery Predicting and Maximizing The Reformate Production in Naphtha Stabilizer Using HYSYS

Ahmed Raheem Hashim and Ala’a Abdulrazaq Jassim

  • Abstract

    The naphtha stabilizer in Al-Basrah Refinery was subjected to simulation and optimization to find the optimum operating conditions by using Aspen HYSYS V7.1. A steady state simulation model is utilized to study the behaviour of multi-component nonideal mixture in the naphtha stabilizer distillation. Optimization results showed that, it’s possible to increase the recovery of C5+ in the reformate from 97 % in actual unit to 99.6 %, also the reformate production increases about (2.383%) from the actual reformate production by changing the design variables and operating conditions. A sensitivity analysis has been used to determine which variable can be used in the optimization tool.

Synthesis, Characterization and Evaluation of Biological Application of Titanium (III) Complexes with Vanillin Schiff Bases

R.Vijayanthimala, G.Brindha, P. Thilagavathi and M. Kavitha

  • Abstract

    Titanium(III) complexes with Schiff base ligands derived from Vanillinand amines(ethylene diamine(en), diethylenetriamine(dien), and triethylenetetramine(trien) have been synthesized and characterized by elemental and thermal analysis, IR, UV-Vis and ESR spectral studies, and magnetic susceptibility studies. Anti-bacterial, Anti-fungal and Anti-cancer activities have also been carried out for these complexes. All the complexes have shown reasonable activity opening up a promising future for vanillin based complexes of titanium (III) in biological field.

Simultaneous Estimation of Moxifloxacin and Betamethasone in Combined Ophthalmic Dosage Form

Ramu Sitharam, Mayank Bapna, Jigisha Patel

  • Abstract

    A simple, rapid, accurate and precise HPLC method has been developed and validated for simultaneous estimation of Moxifloxacin and Betamethasone in combined ophthalmic dosage form. The chromatographic separation was carried out on Hypersil BDS C18 column (100×4.6 mm; 3μ) with mixture of phosphate buffer ph (4.0): acetonitrile (35:65 V/V) as a mobile phase; at a flow rate of 1.0 ml/min. UV detection was performed at 255 nm. The retention time was found to be 3.370 min and 5.70 min for Betamethasone and Moxifloxacin, respectively. Calibration plots were linear over the concentration range of 25-75 μg/ml and 5-15 μg/ml for both Moxifloxacin and Betamethasone, respectively. The method was validated for linearity, accuracy, precision, recovery and repeatability. The proposed method was successfully used for quantitative analysis of Moxifloxacin and Betamethasone eye drops. No interference from the components of pharmaceutical dosage form was observed. Good percentage recovery and low relative standard deviation confirm the suitability of the proposed method for routine estimation of MOX and BETA in pure and ophthalmic dosage form.

Environmental Benign Synthesis of Chromon-4-ones and Benzothiazine Methanones

S.B. Pawar

  • Abstract

    By microwave irradiation of 1-(2-hydroxyl phenyl) 3-(1-methyl 3-n-propyl- 1H-pyrazol-5-yl)-1,3-propan-diones with propionic anhydride in presence of alcohol and triethyl amine gives 2-ethyl, 3 (1-methyl, 3-n-propyl-1H-pyrazol-5 carbonyl) chromon-4- ones and reaction of 1(2-hydroxy phenyl) 3-(1-methyl-3-n-propyl-1H-pyrazol-5-yl)1,3- propan-diones with ortho amino thiophenol in DMSO gives (2-hydroxy phenyl) (3-(1- methly-3-n-propyl-1H-pyrazol-5-yl) -4H-benzo[b][1,4] thiazin-2-yl) methanones

Microwave Assisted synthesis of 1(2-hydroxy phenyl) -3(1, 3-diphenyl-1H- pyrazol-4-yl) -2 (aroyl) -2- propen -1-ones

S.B. Pawar

  • Abstract

    The 1(2-hydroxy phenyl),3-(1,3-diphenyl-1H-pyrazol-4-yl)2-(aroyl) 2- propen -1-ones have been synthesized by condensation of 2-hydroxy 1,3 diketone and 1,3 diphenyl -1H-pyrazol-4-carboxaldehyde by Microwave irradiation method

Study on the Assessment of Adsorption Potential of Dry Biomass of Canna Indica with Reference to Heavy Metal Ions from Aqueous Solutions

Archana Dixit, Savita Dixit and C.S. Goswami

  • Abstract

    Present paper is an attempt to evaluate the adsorption of heavy metals like cadmium (Cd), chromium (Cr), zinc (Zn), and lead (Pb) by the dry biomass of terrestrial plants Canna indica commonly called Saka siri. Very less literature is available for the study on the absorption/adsorption of heavy metals by this plant. The present experimental study was conducted to assess the adsorption capacity of dry biomass of Canna indica to compare and identify their potential to improve the water quality by removing the impurities. Canna indica commonly called Indian shot, it is a perennial plant with rapid growth, height limits to 1.5-2 m. The data on nutrient adsorption/ uptake by dry biomass of Canna indica are not much available. The paper critically evaluates the water – purifying capacity of dry – biomass of this plant basically knows for its ornamental identity. Manuscript will be helpful in showing the water purifying capacity of dry biomass of C.indica and also will evaluate the best results of adsorption shown by varying quantity of the adsorbent.

Synthesis, Spectroscopic Characterization and Antimicrobial Studies of Mononuclear Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) Chelates of Schiff Base Ligand Containing Thiazole Moiety

Naveen Kumar Mawar, Avinash Joshi, Oma Ram and Vimla Chowdhary

  • Abstract

    A series of new coordination complexes of Cu(II), Co(II), Ni(II), Zn(II) and Cd(II) with the Schiff base O-{N-α-(3–methoxy)salicyaldimino}-4-phenylthiazole (HSPT) has been synthesized and characterized by elemental analysis, electrical conductivity measurements, IR spectra, 1HNMR, electronic spectra, magnetic susceptibility , ESR spectra, and thermogravimetric. The Schiff base behaves as tridentate SNO donor ligand and forms the complexes of the type [M(SPT)2] (metalligand) stoichiometry for Cu(II), Co(II) and Ni(II) complexes and [M(SPT)X] stoichiometry for Zn(II) and Cd(II) complexes respectively. The metal chelates exhibit coordination number 4 or 6. The Schiff base and their metal complexes show a good activity against the Gram-positive bacteria; S.aureus, B.subtilis and Gram-negative bacteria; E.coli and fungi A.niger and C.albicans. Also the metal complexes show better antimicrobial results as compared to the Schiff bases.

Adsorption of Malachite Green from Synthetic Waste Water onto Activated Carbon from Corn Cob

Mary Anupama Palukurty, Trivikram Allu, Anil Chitturi and Subba Rao Somalanka

  • Abstract

    Activated carbon which is prepared from Waste corn cob was used as the material for adsorption of the dye malachite green. This dye is widely used in the field of medicine but its release into water bodies can pose to be lethal to flora and fauna. It is also carcinogenic to human beyond certain levels. In the present investigation a trial was made to evaluate the adsorption characteristics of activated carbon from corn cob. The systematic optimization involved study of parameters like- effect of contact time, dye concentration, coke dosage, mesh size variation, pH, temperature and RPM. Langmuir and Fruendlich isotherms were applied to the data obtained at equilibrium. The adsorption capacities (Qm) obtained from the Langmuir isotherms are 52.63, 100, 90.90, 76.92 mg/g at 25, 35, 45 and 55oC respectively. At low temperatures the adsorption was not favorable, but with increase in temperature there was spontaneous adsorption of the dye on the chosen substrate.

Serum Inorganic Phosphorus Level along with Serum Potassium as a Best Marker in the Diagnosis and Prognosis of Chronic Kidney Disease (CKD)

Padmini Habbu, Manjushree Sugoor and Bhagwat Kale

  • Abstract

    Chronic kidney failure is the result of damage to the kidney. This is associated with lack of removal of wastage from the body fluids and hence the waste products accumulate inside the body. Such accumulation of wastage inside the body along with fluid causes oedema in different parts. As a result of this there is a change in biochemical and physiological processes occurring inside. Such changes can be observed with the help of many biochemical markers. Therefore, this work was planned to study the significance of early diagnostic biochemical markers like blood urea, serum creatinine, serum electrolytes and phosphorus in chronic kidney disease.The estimation of blood urea, serum creatinine, phosphorus, sodium and potassium were carried out by using commercial kits for diagnosis on fully automated autoanalyzer. The results were analysed by using students paired‘t’ test. In our study we found a significant elevation (p < 0.001) in blood urea, serum creatinine, serum phosphorus, serum sodium and potassium. Normally, serum phosphorus is not utilized in the diagnosis of renal diseases. But, we found a significant correlation between serum phosphorus level and severity of CKD. Increased serum phosphorus level is associated with increased chances of heart attacks. Thus, serum phosphorus level along with serum potassium level can stand as a best marker in the diagnosis and prognosis of CKD.

Synthesis, Characterization and Antimicrobial Activity of Some 5-Aryl-(2E, 4E)-Pentadienoic Acid Derivatives

Kayed A. Abu Safieh, Manal M.Al-Oqal, Mikdad T. Ayoub, and Muhannad I. Massadeh

  • Abstract

    A number of (2E, 4E)-5-(aryl)-3-methoxypenta-2, 4-dienoic acids (2a-e) have been prepared in good yields by condensation of ethyl (2E)-3-methoxybut-2-enoate with substituted benzaldehyde in KOH/DMSO solution. Similarly, reaction of 2 with benzyl bromide in dry acetone as the solvent and in presence of K2CO3 as a base afforded a series of pentadienoate derivatives (3a-e). Structures of these newly synthesized compounds derivatives were confirmed by IR, 1H NMR, 13C NMR, and MS spectra and by elemental analysis. Moreover, the prepared compounds were evaluated in vitro for their antibacterial and antifungal activities.

Preparation of Titanium Dioxide Nanoparticles and its Application in Wastewater Treatment

S. Kalpagam and T. Kannadasan

  • Abstract

    The discharge of high concentrations of textile dyes is hazardous to the aquatic organisms. Removal of dyes from such wastewaters is a major environmental problem and complete dye removal is necessary because dyes remain visible even at low concentrations. TiO2 nanoparticles are utilized in various applications, the key one being textile dye degradation based on its photocatalytic activity. The aim of the study is to optimize the autoclaving time in the synthesis of TiO2 nanoparticles by the hydrothermal method and test its photocatalytic activity in the degradation of Bromocresol Green and Eriochrome Black T dyes. Samples were prepared by varying the autoclaving time as follows - 5 hours, 7 hours, 1 day and 2 days, at a temperature of 150°C. To check the effect of annealing, fifty percent of the samples were annealed and fifty percent were not. It was observed that among annealed samples, 2 day sample existed in pure anatase phase and highly crystalline compared to other samples, suggesting that longer autoclaving time and annealing result in TiO2 nanoparticles that are more efficient in dye degradation. As the concentration of dye increased, the degradation efficiency decreased. Eriochrome Black T showed marginally better degradation of 97.57% than 96.36% for Bromocresol Green. Recycling of the nanoparticles was 91.35% efficient in degradation. To increase the degradation efficiency further, the TiO2 nanoparticles were doped with Ag and Ni resulting in 98.05% and 97.52% efficiency respectively. The reaction kinetic studies concluded that the degradation process follows first order kinetics. Hence this research leads to the finding that annealing and increasing the autoclaving time of TiO2 nanoparticles during hydrothermal synthesis results in TiO2 nanoparticles that

Magneto, Spectral and Thermal Studies of Lanthanum and Lanthanides (III) Nitrate and Perchlorate Complexes of 2-Benzoylaminopyridine N-Oxide

Sunil Kumar Gupta and Amar Srivastava

  • Abstract

    2-Benzoylaminopyridine N-oxide (BzAPO) complexes of lanthanide nitrate and perchlorate of the formula LnX3.nBZAPO (where X = NO3 - or ClO4 - ; n = 2, 4; Ln = La, Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho or Yb) have been prepared and characterized by elemental analysis, molar conductance, molecular weight, magnetic measurement and IR spectral data. Thermal properties have also been studied. The decomposition temperature of these complexes indicates that the nitrate complexes are more stable than perchlorate complexes. The IR spectral data reveals that BzAPO behaves as bidentate ligand and forms a seven membered stable chelate ring. A tentative coordination number of 10 and 8 has been assigned for nitrate and perchlorate complexes, respectively.

Electrochemical and Biological Studies of Complex of Nickel (II) with a 2,5-Bis(2-pyridyl)-1,3,4-thiadiazole

Y. Baba Hamed, T. Attar, Y. Harek, H. Merzouk, L. Larabi

  • Abstract

    The synthesis and characterization of 2,5-Bis(2-pyridyl)-1,3,4-thiadiazole (L1) derived from Hydrazine and 2-Pyridinecarboxaldehyde and their Ni(II) complexes are reported. The electrochemical behavior of the Ni(II) complexes was investigated in DMSO by cyclic voltammetry using hanging mercury drop electrode (HMDE). The obtained results showed that the complexes displayed Ni(0)/Ni(II) couples irreversible waves A biological study was also carried out to determine the in vitro effects of different concentrations of nickel complexes of the ligand (L1) on the proliferative response of human mitogen-stimulated lymphocytes.

Synthesis, Characterization and Biological Activities of Some Novel Substituted Pyrimidine

Derivatives

Raj Neelam,Rajput Manojkumar, V.Jayadevaiah, Sahoo Subhas, V Gupta Ram Mohan

  • Abstract

    Pyrimidine” derivatives are an important class of heterocyclic chemistry and reported to possess a wide spectrum of biological activities such as, antibacterial,anti-inflammatory, antihypertensive, antitumor, and calcium channel blocking activity. Present work is based upon Bigenelli reaction which involves one pot- condensation of an aldehyde, ethylacetoacetate and urea in ethanolic medium in the presence of strong mineral acid in 1893. This method has drawback i.e. lower yield and longer reaction time. Especially with aliphatic as well as substituted aromatic aldehydes.Urea or thiourea react with furfuralaldehyde p-chloro- benzaldehyde in presence of ethanol as a solvent to get 5-acetyl-4-(furan-2-yl) -6-methyl-3,4-dihydropyrimidin- 2(1H)-one which upon reaction with various aromatic aldehyde gave pyrimidine derivatives(Chalcones), respectively. The structures of these compounds are confirmed by IR, 1H-NMR and Mass Spectral data. The newly synthesized compounds have been evaluated for their antifungal and antibacterial activities.

Synthesis and Comparative Study of Calcium Zincate Nanoparticles for their  Decolourization Efficiencies against Disperse Blue 2BL di azo dye in Presence of Sun light

Bhavya.C, Yogendra.K and Mahadevan.K.M

  • Abstract

    The photocatalytic decolorizing efficiency of two synthesized Calcium Zincate nanoparticles (CaZnO2 I and CaZnO2 II) against Disperse Blue 2BL dye in aqueoussolution was investigated. The Calcium Zincate nanoparticles were synthesized by simple solution combustion method using two different fuels- urea and acetamide. The synthesized nanoparticles were characterized by Scanning Electron Micrograph (SEM),X-Ray Diffraction (XRD). The band gap was determined by using UV-absorption spectroscopy. All the experiments were conducted in presence of sun light. Degradation efficiency was studied by varying different parameters such as catalyst concentration, solution pH and dye concentration. The CaZnO2 I proved to be very efficient in which ~100% decolorization was achieved of 30ppm dye solution at pH 9 with respect to time interval of 120minutes with 37.08mg/L reduction in COD. 

Synthesis, Characterization and Application of a Novel Schiff Base

Sowkath A, Mansur Ahmad, Anbarasan R

  • Abstract

    A Schiff base (SB) between ortho carboxy benzaldehyde (OCB) and diamino diphenyl methane (DADPM) was synthesized at 70o C at nitrogen atmosphere under stirring conditions for 5 hours. Thus obtained colorless product was subjected to initiate ring opening polymerization (ROP) of ε-caprolactone (CL) at various [M/I] such as 10, 50, 100, 200 and 400. The polymerization of CL by SB was confirmed by FTIR, GPC, SEM, TGA and DSC like analytical tools. While increasing the [M/I] the FTIR relative intensity was increased due to less availability of number of initiating sites 

Constituents of Tephrosia Purpurea

Jagdish P. Singh, Abhimanyu Yadav, Vibha Singh and Pratiksha Singh

  • Abstract

    Two flavones and one glycoside have been isolated from stem of T. Purpurea and their structures were established by spectral evidences. One flavone named as 2'', 2''-dimethyl-7, 8-pyranoflavone and second as 3, 5, 4'-thrihydroxy-6, 7-dimethoxyflavone are found to be known compounds from other species of T. Purpurea. The glycoside was identified as 3, 5- imethoxycinnamylalcohol-4-O-B-D-glucopyranoside.

Schiff’s Base Ligands and Their Transition Metal Complexes as Antimicrobial Agents

Pallavi Goel, Dinesh Kumar, Sulekh Chandra

  • Abstract

    Schiff’s base ligands and their transition metal complexes comprise miscellaneous  herapeutically potent applications in the field of medicinal chemistry and synthetic applications in the field of the organic and inorganic chemistry. This review includes synthesis of Schiff’s base ligands and their transition metal complexes (Mn (II), Cu(II), Ni(II) and Co(II) metal ions) and an appropriate balance between the broad spectrum pharmacological profile. This study overview, collecting the most significant strategies adopted in last few years to design promising antimicrobial transition metal complexes of schiff’s bases which would be a help to the working scientists or researchers in the biological field and is expected to hopefully produce analogues with better biological profiles and with the minimal requirement to maintain the activity.

Heterobimetallic Complexes of Nickel (II), Lead (II), Cobalt (II) and Copper (II) With Diethylene Triamine Penta Acetic Acid (DTPA): Equilibrium Studies

Meena Devi, R. Nair (Ahuja), Seema Kumari Yadav and K. Dwivedi

  • Abstract

    Heterobimetallic systems involving DTPA have been investigated potentiometrically in aqueous medium under the well-defined condition of temperature and ionic strength. SCOGS computer program is used to obtain the speciation of various protonated, nonprotonated binary and ternary species formed in a particular equilibrium. The percentage formation of heterobimetallic complexes is appreciably high which is evident from speciation curves. The stability constants and thermodynamic parameters ΔG˚, ΔH˚, and ΔS˚ support the favourable formation of mixed metal species.Negative values of ΔlogK indicates higher stability of ternary species .

A Green Synthesis and Characterization of Erythrina variegata Decorated Silver Nanoparticles

Mari Selvi J, Murugalakshmi M, Anbarasan R

  • Abstract

    The bio-synthesis of nanoparticles (NP) has been proposed as a cost effective and environmental friendly alternative to chemical and physical methods. Plant mediatedsynthesis of NPs is a green chemistry approach that interconnects nanotechnology and plant biotechnology. In the present study, synthesis of silver NP has been demonstrated using extracts of Erythrina variegata leaves. Thus obtained Ag NPs were characterized byFTIR spectroscopy, UV-visible spectroscopy, XRD, SEM and AFM analysis. The XRD pattern showed the characteristic Bragg peaks of d111, d200, d220 and d311 facets of the face centered cubic (fcc) silver NP and confirmed the crystalline nature of Ag NP. The different types of biomaterials presented in the Erythrina variegata extract synergistically reduce the Ag metal ions via polyol methodology, as each one is unique in terms of its structure and its function. This work proved the capability of biomaterial towards the synthesis of silver NPs with less polydispersity of shape and size. 

Thermodynamic Studies of Depolymerization of Polyethylene Terephthlate (PET) Waste

Vishvanath S. Zope and Narendra A. Ghule

  • Abstract

    Nowadays the Poly-ethylene terephthalate (PET) is one of the most commonly used synthetic polymers due to the growing application as an engineering plastic. PET waste taken from post-consumer soft drink bottles was subjected to chemical recycling process such as, alkali hydrolysis using sodium hydroxide. Viscosity average molecular weight of The PET waste study was determined by Ostwald method and recorded as 7338. The product obtained in de-polymerization of PET waste is a value added product such as terephthalic acid (TPA). The reactions were studied at different temperature ranging from 373 to 463K and time between 20 to120 minutes. The purified products was characterized by recording its IR and melting point. The velocity constant of depolymerization reaction obtained by measuring the weight of unreacted PET is in the order of 10-3 min-1. Thermodynamic parameters such as enthalpy of activation (ΔH), free energy of activation (ΔG) and entropy of activation (ΔS) for sodium hydroxide at 373K were found to be 20.02 KJmol-1, 1.63x10-3 KJmol-1 and 0.053 KJmol-1respectively. Similar thermodynamic study has been carried out for depolymerization reaction with catalysts like lead acetate and pyridine.

The study of Excess Molar volume and deviation in viscosity of binary mixtures of Ethyl Propionate in Butanol-1 and Pentanol-1 at 308 K Ultrasonically

R.C.Verma and Vinod Kumar Yadav

  • Abstract

    Density, Ultrasound velocity and viscosities of Ethyl propionate with butanol-1 and  pentanol-1 have been measured over entire range of composition at 308 K and atmospheric    ressure.The computed acoustic and thermodynamic properties of Ethyl propionate in higher alcohols will give the excess values of essentropic compressibility,molar volume and viscosity. The excess value wills decied the nature and extent of molecular interaction of Ethyl propionate in butanol-1 and pentanol-1

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