Vol. 7 & Issue 2 ; Section A : Chemical Sciences

Date : Feb. to April 2017

 

Beneficiation of Low-Grade Phosphate Ore Using Desliming and Gravity Separation Technique

Hanaa A. El- Boraey, Ashraf A. El-shennawy, Ahmed M. Masoud, Hady S.Gado4 and Ahmed A.Bekair

  • Abstract

    Gravity separation technique has been adopted to upgrade the Egyptian low-grade phosphate ore (22.71%) from East Siba'eya area as an alternative method to the existing calcination method, which is not friendly environment and has several disadvantages and low reactivated final product. Shaking table is a gravity separation device was used for separating phosphate ore with respect to the factors influencing effective mineral separation include particle size, density and shape, riffle design, deck shape and slope, water flow, feed rate shaking motion and speed. Prior to gravity separation experiments, the feed phosphate ore was prepared by washing and desliming to remove fine clay from ores. The phosphate concentrate obtained under the optimum conditions (particle size was less than 150 mesh (100 μm), the optimal deck slope of shaking table was 10°, the optimal feed water flow rate was 8 liters per minute and the dressing water flow rate was 10 liters per minute. The results show promise for the produced grades of 29%–33% P2O5 with 68.51% recovery.

Molecular Charge-Transfer Complex between Thymol Drug and Bromocresol purple

Asmaa A. Ibrahim, E.H.El-Mossalamy and S.Abdel-Aal

  • Abstract

    The charge-transfer complex of the thymol (TY) {2-isopropyl-5-methylphenol} Drug with {4,4’-(1,1-Dioxido-3H-2,1-benzoxathiole-3-ylidene)- bis(2-bromo-6-methylphenol)} Bromocresol purple (BCP) were studied spectrophotometrically in different solvents. Using application Benesi-Hildebrands equation, molar extinction coefficient (εCT), the equilibrium constant (KCT) and thermodynamic parameters were estimated. The geometric parameters, electronic properties and molecular electrostatic potential were calculated. Elemental analyses (CHN) IR, UV–Vis techniques investigation were used to characterize and conforms the molecular structure of thymol CT-complex. Quantum chemical calculations have been carried out by using density functional theory and time-dependent density functional theory calculations.

 T3P mediated one pot  synthesis of quinazoline derivatives  and evaluation of their evaluation of their mesomorphic studies 

Mahendra K .R.Tanuja S. B., Sowmya P. T. and K.M.Lokanatha Rai

  • Abstract

    The substitution of the Ketones, benzaldehydes and component with an alternative functional group and reagents has not been reported so far. Consequently, the progress of an easy and stable replacement for these ketones or benzaldehydes by using low-cost and willingly accessible reagents would broaden the compass of the reaction in organic synthesis. Newly, Microwave irradiation has received the significant notice owing to their function in the preparation of quinazolines. As the review of the literature of the quinazoline derivatives, majority of the research comprises the biological and pharmacological activity. To diverse the investigation of quinazolines; here we reported the quinazoline derivatives by replacing the dipoles by taking functional group diverse aldehydes and these exhibits the considerable properties of mesomorphic studies and are reported in the present work.

Preparation and mesomorphic properties of new liquid crystalline 4,5-Diaryl 2H-[1,2,3]-triazole derivatives

Sowmya P T , Mahendra K R , Lokanatha Rai K M

  • Abstract

    Two homologous series of 4,5-disubstituted 2H-[1,2,3]-triazole derivatives were synthesized from chalcones, sodium azide and CuI as catalyst via oxidative cycloaddition reaction, flexibility in the synthesized molecules was provided by attaching different straight alkoxy chains with various n-alkyl bromides (n=4 -8,10, 12, 14, 16, 18). The synthesized compounds were characterized on the basis of 1H NMR, 13C NMR, LC-MS and by elemental analysis. The melting point, transition temperatures and liquid crystal morphologies were determined by polarizing optical microscopy (POM) in conjunction with a hot stage and by differential scanning calorimetry (DSC).

Synthesis, Characterization and Thermo-Acoustical properties of 3-phenyl-1- (4-chlorophenyl) prop-2-en-1-one at different temperatures

Balaji A. Gop and Sitaram K. Chavan

  • Abstract

    3-phenyl-1- (4-chlorophenyl) prop-2-en-1-one have been synthesized and characterized by Melting Point, Infrared spectroscopy, Thin Layer Chromatography, and H1 NMR data. The density, viscosity, ultrasonic velocity and refractive indices of mixed solvents 0-100% (by wt.) of 3-phenyl-1- (4-chlorophenyl) prop-2-en-1-one have been measured at three different temperatures 298, 303, 308, 313, 318K. The experimental data obtained was used to calculate various acoustical parameters such as Acoustical impedance (Z), adiabatic compressibility(β),intermolecular free path length(Lf), Molar volume (Vm), Free volume (Vf) , Internal Pressure (𝜋i) Rao’s molar sound velocity (Rm) Absorption Coefficient(α/f2) Mole Fraction (X), Effective Molar Mass (Meff), Viscous Relaxation time (τ) and Gibb’s Free Energy Change (Δ𝐺) These parameters are interpreted in terms of solute- solute and solute- solvent interaction and its effect on mixed solvents system.

Characterization of a New Zn2+ion Selective Electrode Based on Zn Ammonium Phosphate as Electro Active Species

Shaziya Mohammed IrfanMomin, PramodaSasidharan Pillai and Dr Nahid Azam

  • Abstract

    A new Zn 2+ ion selective electrode based on zinc Ammonium Phosphate as an electro active species was prepared. Potentiometric responses revealed that this new electrode has good selectivity to Zn2+ relative to some other cations. With the optimal membrane compositions, the electrode based on this new ionophore reveals a good Nernstian behavior over wide concentration ranges of 1.0×10-5—1.0×10-1M with a detection limit of 1.0×10-5 M Zinc ion concentration. The electrode possesses advantages of low resistance and very fast response time. The potentiometric responses (pH range 3.0 – 5.0) are independent of the pH of the test solution.

Synthesis and Characterisation of Antibacterial Silver Nanoparticles

Zainab TY Al-Abdullah, Zainab Al-Shuhaib, Amel Salih abdulridah and Maitham Najim Aboud

  • Abstract

    D (+) lactose was used in this study for the synthesis of silver nanoparticles which offered an economical and green synthetic route relative to expensive and toxic chemical methods. The UV–Vis was used to monitor the silver nanoparticles formation, which was apparently formed within 3 min with evidence of surface plasmon bands (SPB) at 420 nm. The crystals were equally characterized using, X-ray diffraction methods.XRD spectra showthe silver nanocrystallites. Moreover, SEM images show the size and the shape of silver nanoparticles. Moreover high electrolytic conductivity of silver nanoparticles was observed. The sample was further screened against Staphylococcus aureus and Escherichia coli. From the results, there is evidence of inhibition towards bacteria growth. The green synthesis method was compared with the chemical reduction method using Tollen's reagent about inhibition towards bacteria growth. The best activity was observed for suspension reduced with Tollen's reagent

Synthesis of pyrazole-pyrazolone, triazole

Syed Nazimuddin and Maqdoom Farooqui

  • Abstract

    In the present work, a simple convenient and high yielding synthetic route has  been employed for the synthesis of targeted molecules synthesis of n-[3-marcapto-5-(2-propyl benzimidiazol-1-yl methyl)-[1, 2, 4] triazole-4-yl] acetamide. The structures were confirmed by elemental analyses, H1NMR, and physical properties. The synthesized compounds were screened for anti-microbial analysis against E. coli, B.cereus,S.cerevisae and A. niger. The compounds are found to be highly active, henceforth, could be attractive lead molecules for developing new therapeutics against tested microorganisms.

Leaf Epicuticular Wax Composition of Tamarix nilotica from Sudan

Bader Omer Burham, Hatil Hashim EL-Kamali, Nashwa Abdalla Abu Aaglaa, Samah Omer Essa Omer

  • Abstract

    Leaf epicuticular wax chemical composition was studied in Tamarix nilotica. The principle components of the wax were alkanes (2.04%), alkane containing sulfonyl chloride (80.38%), alkene (2.36%), esters (1.18%), ethers (3.18%) and phenol (3.95%). A total of 34 compounds were detected in the n-hexane crude extract of Tamarix nilotica examined. The compound identified, formula, retention time, and percentage yield. About 80% of the total isolate is alkane containing sulfonyl chloride, 1-Hexadecane-sulfonyl chloride, the major compound identified from T. nilotica. Other major constituents are 3-methylphenol (3.95%), ethylisopropyl ether (3.18%) and (Z)-pentatriacont-17-ene (2.36%). Others are recorded in minute quantities. The components reported in this work have not been reported in literature before.

Computational Calculations of Chitosan Fragments as Corrosion Inhibitors of Metals

Ghassab M. Al-Mazaideh, Khaleel A. Abu-Sbeih, Salim M. Khalil

  • Abstract

    DFT was used to calculate the anticorrosion activity of several chitosan fragments on Fe, Al and Cu. The global quantum parameters and Gibbs function of adsorption ΔGads of inhibitors on metals have been calculated. The results showed spontaneous physical and nonspontaneous chemical adsorption of the inhibitors on the metals. The inhibitor efficiency was found to be in the order pentamer > tetramer > octamer > hexamer > trimer > dimer > heptamer > monomer. The calculated fraction of transferred electrons (ΔN), global electrophilicity index (ω) and dipole moment (μ) for the adsorption of inhibitors on the surface of the metals (Fe, Al and Cu) in the gas phase showed that the pentamer has the highest anticorrosion inhibition of all fragments. The order of the inhibition efficiency on the metal’s surface is in the order: Cu > Fe > Al. As a result, the pentamer is the best inhibitor for Cu surface. This agrees with previously published experimental results.

Synthesis, characterization and BSA interaction studies on Co(III) and VO(IV) complexes of 2-[(Benzo[1,3]dioxol-5-ylmethylene)-amino]-pyridin-3-ol

Savithri K, B C Vasantha Kumar and H D Revanasiddappa

  • Abstract

    A new bidentate imine-based ligand 2-[(Benzo[1,3]dioxol-5-ylmethylene)-amino]-pyridin-3-ol (HL) and its complexes of Co(III) and VO(IV) were synthesized by physicochemical, analytical and spectral measurements. The synthesized ligand and its complexes were screened for antimicrobial and antioxidant assay. Interaction of synthesized compounds with bovine serum albumin (BSA) was investigated using fluorescence, absorption spectroscopy and non-radiative energy transfer techniques. The result shows that complexes cause the fluorescence quenching of BSA through a static quenching process. The binding constant (Kb) for the formation of a complex between compounds and BSA at 298 K are found to be in the range 1.03-2.61×105 mol-1L.

Thermodynamic Behaviors of Hypersensitive Transition Observed In Some Praseodymium Doped Systems with Various Amide Group Containing Ligands

Suresh Purohit

  • Abstract

    In the present research paper we have studied the thermodynamic behaviors of hypersensitive transition observed in some praseodymium doped system with alcoholic saturated solutions of amide group containing ligands. For this purpose we have choose three ligands i.e., Paracetamol, Indomethacin and Lidocaine. These ligands are drugs in nature and contain amide group. It has been observed that amide group containing ligands play very important role in biological chemistry, since proteins made up of amino acids which contain amide group in their structure. Study is based on doped crystal phenomenon. In this research paper we have choose thermodynamic efficiency (TET) and work function (A) of hypersensitive transition. Both of these parameters are very important to explain the stability of a complex. Uses of computational chemistry have been explored in order to develop better and easier methods of calculations.

Synthesis, spectral characterization and antimicrobial activity of selected transition metal (II) Complexes using Salicyaldehyde with 4-methoxyaniline moiety

Vishal G. Shinde, Vijayanand D. Ingale, Dayanand M. Suryawanshi, Anjali S. Rajbhoj, Suresh T. Gaikwad

  • Abstract

    The synthesis of new divalent Schiff base on the transition metal (II) complexes like Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) were derived by the condensation of Salicyaldehyde with 4-methoxyaniline in alcoholic medium with forming 2-(E)-(4-methoxyphenylimino) methyl phenol. The structures of the Schiff base ligands and transition (II) metal complexes have been proposed by the analytical and spectral data by FTIR, 1H-NMR, X-ray diffraction and Magnetic studies. The XRD studies indicate that monoclinic crystal system for Ni (II) complexe. Antifungal activity was found for Mn(II) and Zn(II) Schiff base complex against the species Aspergillus niger higher activity than that of Schiff base ligand and standard drug like Fluconazole at the same concentration 500 ppm.a

Quantum chemical studies and Adsorption Characteristic of Acetylpropionyl Mild Steel in Hydrochloric Acid Solution

Hassan El attari, Salim Mengouch and Khalil Chefira

  • Abstract

    The purpose of this paper is to study the inhibition of the corrosion of mild steel C38 in 1M HCl solution by Acetylpropionyl (ACTP) has been investigated by using weight loss, potentiodynamic polarization, and electrochemical impedance spectroscopy measurements. Results obtained revealed that the inhibition efficiency increased with the increase in concentration of ACTP but decreased with the increase in temperature. Inhibition efficiencies obtained ranged between 47, 67 to 87, 20 % in the concentration range of 1. 10-3 to 5. 10-3 M/L. It appears that this compound inhibits mild steel corrosion by affecting both cathodic and anodic reactions. Electrochemical impedance studies show that charge transfer resistance increases with concentration of inhibitor and that it controls the corrosion process. El-Awady adsorption isotherm was found to fit well with the experimental data. Values of free energy of adsorption indicates that the adsorption of ACTP on the mild steel surface involves the physical adsorption process. Both thermodynamic and activation functions of dissolution and adsorption processes were calculated and discussed. Quantum chemical parameters were also studied and determined.

Development and Validation of UV/Vis. Spectrophotometric Method for Determination of Clarithromycin

Zehra Ashraf, Somia Gul and Faazia Qaazi

  • Abstract

    An easy, precise, sensitive, reproducible, cost-effective spectroscopic method was developed and validated for the estimation of Clarithromycin. This method obeys Beer’s Law in concentration ranges of 0.1-0.8 mg.mL−1for Clarithromycin. This method was validated for parameters linearity, accuracy, precision and ruggedness as per ICH guidelines. The λ max of Clarithromycin was 205 nm in methanol. The drug follows linearity in the concentration range 0.1-0.8 mg.mL−1 with a correlation coefficient value of 0.995. The accuracy of this method was tested by recovery method implemented at three different levels, i.e., 120%, 100%, and 80%. The method of precision was studied as an intra-day; inter-day variations & repeatability. The %RSD value is less than 2 (< 2) which indicates that the method is precise. Ruggedness method was studied with the aid of two different analysts. This method can be recommended for the routine quality control and quantitative analysis of Clarithromycin.

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