Vol. 7 & Issue 3 ; Section A : Chemical Sciences

Date : May 2017 to July 2017

 

The relation between van der Waals parameters a, b and a simpler calculation formula of molecule potential energy

Zhuxin Wu

JCBPS; Section A; May 2017 – July, 2017, Vol. 7, No. 3; 501-509.

[DOI: https://doi.org/10.24214/jcbps.A.7.3.50109]

  • Abstract

    In this paper, the writer derived a formula  T= 8a/27Rb from the isotherms of van der Waals formula which could be used in van der Waals formula.From the formula of a and b, the formula of the depth of molecular potential well was deduced Φ0 = 27/8 . k T which showed the depth of molecular potential well was only relative and proportional to the temperature. By analysis on this formula the writer deduced a relation V =  - 27/8 kT (r0/R)6 that was an easier formula to calculate molecule potential energy between two same molecules. By considering this formula and London dispersion formula, the author did a test on the correctness of formula V =  - 27/8 kT (r0/R)6, and the test showed the formula was correct and accurate which also showed the correctness of other new formulas in this paper.

Nanomaterial and their applications in Environmental sample preparation techniques: A Review

Abiyot Kelecha Geletu

JCBPS; Section A; May 2017 – July, 2017, Vol. 7, No. 3; 510-524.

[DOI: https:/doi.org/10.24214/jcbps.A.7.3.51024]

  • Abstract

    In this paper the use of both carbon based and metallic nano particles in separation and extraction of environmental samples, method of synthesis and modification is reviewed. Their use in preparation procedures for sample clean-up and preconcentration of analytes is a topic of growing interest in analytical chemistry. The properties of nanomaterials have been extensively exploited in different separation and enrichment techniques (e.g., SPE, microextraction and filtration). Nanomaterials can be used in different formats as single particles, aggregates, or powders or dispersed in a matrix. The aim of this paper is to present the recent application of nanomaterials in sample preparation procedure for sample clean-up and preconcentration of the analytes, which allow simplification of the method and the possibility of treating small amounts of sample.

Synthesis of novel pyridine linked to benzimidazole via sulphide and their Antioxident and Antimicrobial activity

Sathish Byrappa1, K.R.Mahendra, B. Ashwini, Puttananjaiah Shilpa, K. M. Lokanatha Rai

JCBPS; Section A; May 2017 – July, 2017, Vol. 7, No. 3; 525-535.

[DOI: https: //doi.org/10.24214/jcbps.A.7.3.52535]

  • Abstract

    In this communication, we synthesized a series of eleven novel 2-(2-(1H-benzo[d]imidazol-2-ylthio) ethyl)-3-methyl-4 H-pyrido [1,2-a] pyrimidin-4-one analogues, characterized using various spectroscopic techniques and evaluated for their antioxidant and antimicrobial activities. Among the tested compounds, compound 8d and 9 shows good antioxidant activity and compound 8d shows excellent antibacterial activity.

Homolytic phosphorylation of unsaturated compounds as a method for the synthesis of organo-Phosphoric

Elégbede A. Félix, Atchade Bardieu and Elégbede N. Bernadin

JCBPS; Section A; May 2017 – July, 2017, Vol. 7, No. 3; 536-546.

[DOI: https://doi.org/10.24214/jcbps.A.7.3.53646]

  • Abstract

    In the structure of olefin, the introduction of halogen, of alkoxy groups acyl and other, influence the process of homolytic addition and performance in the phosphonates. The movement of the double bond toward the center of the molecule of olefin (composed non- saturated) makes it difficulté. The Addition (2-hexene, 2- heptene compared to 1-hexene and 1-heptene) and the cyclohexene is less reactive. The addition of the phosphite in diethyl cyclohexene initiated by UV rays is characterized significantly by the effect of induction. The introduction of the halogen atom (chlorine, fluorine, etc.) increases the reactivity of the olefin. As well as the vinyl chloride reacts with the phosphite of dimethyl to 145-155°C in the presence of peroxides of the alkyl to give β-chloroethyl dimethyl phosphonate with the yield
    85%.

    Resume : La structure de l’oléfine, l’introduction d’halogène, de groupes alcoxyacyle et autres, influencent le déroulement du processus d’addition homolytique et le rendement en phosphonates. Le mouvement de la double liaison vers le centre de la molécule d’oléfine (composé non- saturé) rend difficile l’addition (2-hexène, 2- heptène comparés à 1-hexène et 1-heptène). Le cyclohexène est moins réactif. L’addition du phosphite de diéthyle au cyclohexène initié par les rayons UV est caractérisée de façon significative par l’effet d’induction. L’introduction de l’atome d’halogène (chlore, fluor, etc.) augmente la réactivité de l’oléfine. Ainsi le chlorure de vinyle réagit avec le phosphite de diméthyle à 145-155°C en présence des peroxydes d’alkyle pour donner β-Chloroéthyle diméthyle phosphonate de rendement 85%.

Potential Biological Activities, Molecular Docking and Synthesis of Novel Ag+, Ni +2 and Fe+3 Complexes with Schiff base N'-(1-(4-((3,4-dihydroquinolin-1(2H)-yl)sulfonyl) phenyl) ethylidene)-3-oxo-3H-benzo[f]chromene-2-carbohydrazide

Mahmoud Sayed Bashandy, Sami Abdullah Al-Harbi, Amr M. Nassar, Shimaa Mohamed Abd El-Gilil

JCBPS; Section A; May 2017 – July, 2017, Vol. 7, No. 3; 547-562.

[DOI:10.24214/jcbps.A.7.3.54762]

  • Abstract

    Ag+, Ni+2 and Fe+3 complexes with Schiff base N'-(1-(4-((3,4-dihydroquinolin-1(2H)-yl)sulfonyl)phenyl)ethylidene)-3-oxo-3H-benzo-[f]chromene-2-carbohydrazide (HL) have been synthesized. The structure of the new complexes is established using spectroscopic, elemental and thermal analysis. The data reveals that the geometry of the complexes are dihedral for Silver complex, square planar for Nickel complex and octahedral for Iron complex. The ligand molecule is found to be acts as bidentate with complex 1 through carbonyl oxygen and enol form oxygen and tridentate with complexes 2 and 3 via carbonyl oxygen, enol form oxygen and azomethine nitrogen. The structures of the newly synthesized compounds were confirmed by elemental analysis, IR, UV, TGA and Ms spectral data. The in vitro antimicrobial activities of ligand and their complexes were tested. Ni (II) complex showed a significant activity against all microorganisms. Fe (III) complex exhibits a significant activity against Mycobacterium tuberculosis. In addition, in vitro cytotoxic activities of all the synthesized compounds were evaluated on human liver carcinoma HEPG2 and human prostate carcinoma PC3 cell lines. HL, ligand exhibited a significant inhibition against HEPG2 with IC50 value 178.21 μM. while, Ag(I) and Ni(II) complexes exhibited a significant inhibition against PC3 cell line with IC50 values 4.39 μM., and 10.68 μM., respectively compared to MTX as a reference drug. Docking studies involving MOE (Molecular Operating Environment) was studied to find the potential binding affinities between the ligand and the DHFR enzyme. HL and Ni (II) complex showed more interaction with DHFR which lead to inhibit this enzyme.

Colorimetric determination of vitamin C using Fe(II)-5-Chloro-7-iodo-8-hydroxyquinoline complex

Ashwani Kumar, Brij Mohan and Pankaj Bhatia

JCBPS; Section A; May 2017 – July, 2017, Vol. 7, No. 3; 563-571.

[DOI: 10.24214/jcbps.A.7.3.56371.]

  • Abstract

    An extractive spectrophotometric procedure based on the complexation of reduced Iron (II) with 5-Chloro-7-iodo-8-hydroxyquinoline (CIHQ) for the estimation of micro amounts of vitamin C is described. The resulting complex is extracted into chloroform to give a reddish brown extract which shows an absorption band at 485 nm. Linear relationship between absorbance and concentration of ascorbic acid is observed up to 0.8 μg ml-1. Interference studies of different substances including sugars, vitamins and amino acids, metal ions and organic acids were carried out. The utility of the method was tested by analysing some of the marketed products of vitamin C.

Chemical composition, Elements and Photochemical contents of Trigonella foenum-graecum L. (Seeds)

Bader Omer Burham

JCBPS; Section A; May 2017 – July 2017, Vol. 7, No. 3; 572-578,

[DOI: 10.24214/jcbps.A.7.3.57278]

  • Abstract

    The objective of this study is to investigate the chemical composition, minerals and photochemical contents of Fenugreek seeds which obtained from Albaha, KSA (Panda market). The analysis of chemical composition of fenugreek shows that the percentage of dry matter , Ash, protein, oils ,fiber and total carbohydrates were 89.77, 0.28, 29.7, 7.13, 6.28 and 46.32,respectively. Minerals contents were Ca (43.93mg/100g), Fe (11.17mg/100g) and P (698.21mg/100g).The contents of photochemical ( phytic acid, tannin and total polyphones) were 152.91, 1.32 and 452.12mg/100g, respectively.

Electrochemical Self Assembled Monolayer based sensor for Sodium ion using 4-aminobenzo-15-crown-5 as ionophore

Urvasini Singh and Sunita Kumbhat

JCBPS; Section A; May 2017 – July, 2017, Vol. 7, No. 3; 579-585.

[https: 10.24214/jcbps.A.7.3.57985].

  • Abstract

    A novel sodium ion (Na+) selective sensor based on gold surface functionalized by immobilization of ionophore, 4-aminobenzo-15-crown-5 (4-AB-15-C-5) through a self-assembled monolayer has been developed. Host-guest complexation of lithium ions and ionophore was confirmed by conductance studies, UV-Vis and FTIR Spectroscopic measurements. The binding of sodium ion to the ionophore at sensor surface was monitored using a redox probe Ru(NH3)63+ / Ru(NH3)64+as ‘reporter ion’ employing cyclic voltammetry and differential pulse voltammetry. The sensor was found to be responsive 1mM Na+.